do not reach the LDL-C guideline-recommended target of <70 mg/dL12,13
Statins, along with diet and exercise, are often not enough for many patients to reach their recommended target.9-11
Additional treatment options may be
needed to effectively help patients lower
their LDL-C and reach their target.
-
PERSISTENTLY
ELEVATED
LDL-C -
LOW
STATIN
TOLERANCE -
HIGH
TREATMENT
BURDEN
Paul is post-event
with persistently
elevated LDL-C
Not a real patient.
He is a retired mechanic who loves fishing with his grandchildren.
He does low-impact exercise a couple of times a week, tries to watch
what he eats, and sees his health care provider twice a year.
Paul feels discouraged by the daily demands of his treatment plan,
but remains relieved he managed to bring his LDL-C down after his
myocardial infarction (MI).
He is a retired mechanic who loves fishing with his grandchildren. He does low-impact exercise a couple of times a week, tries to watch what he eats, and sees his health care provider twice a year. Paul feels discouraged by the daily demands of his treatment plan, but remains relieved he managed to bring his LDL-C down after his myocardial infarction (MI).
Age: 65
Insurance: Medicare
LDL-C level: 110 mg/dL
BMI: 36 kg/m2
Currently on maximally
tolerated dose of
atorvastatin (40 mg)
Medical history:
-
CV events: MI 2 years ago, coronary artery bypass surgery (CABG)
-
Additional health conditions: type 2 diabetes and hypertension
I am doing everything I can—
taking my pills,
watching my
diet and exercising—but my
cholesterol
is still not low
enough. What more can I do?
WOULD YOU CONSIDER
LEQVIO FOR PATIENTS
LIKE PAUL?
June has
persistently
elevated LDL-C
with low statin
tolerance
Not a real patient.
She is an accountant who enjoys going to local sports games with her family. She sees her health care provider 1-2 times a year, but is not overly worried about her LDL-C and often "cycles" on and off her statin because of side effects. June likes things as they are and doesn't want to increase her daily medications.
She is an accountant who enjoys going to local sports games with her family. She sees her health care provider 1-2 times a year, but is not overly worried about her LDL-C and often "cycles" on and off her statin because of side effects. June likes things as they are and doesn't want to increase her daily medications.
Age: 57
Insurance: Commercial
insurance
LDL-C level: 95 mg/dL
BMI: 28 kg/m2
Currently on maximally
tolerated dose of
rosuvastatin (20 mg)
Medical history:
-
CV events: diagnosed 5 years ago with unstable angina, experiences chest pains
-
Additional health conditions: long-standing hypertension, family history of CVD
I want to take my statin
every day, but sometimes
the side effects get in the
way. Instead of
increasing
my statin, is
there another option?
WOULD YOU CONSIDER
LEQVIO FOR PATIENTS
LIKE JUNE?
Christine is
post-event with
multiple
comorbidities
and overburdened
by treatment
Not a real patient.
She is a retired elementary school teacher who lives for visiting her new granddaughter. Though she sees her health care provider every 3-6 months, she struggles with adherence and managing her comorbidities and finds it difficult to exercise and eat healthy due to limited time and resources. Christine is overwhelmed by the demands of her current treatment plan and her overall pill burden, while living with the frustration of a lack of treatment success.
She is a retired elementary school teacher who lives for visiting her new granddaughter. Though she sees her health care provider every 3-6 months, she struggles with adherence and managing her comorbidities and finds it difficult to exercise and eat healthy due to limited time and resources. Christine is overwhelmed by the demands of her current treatment plan and her overall pill burden, while living with the frustration of a lack of treatment success.
Age: 69
Insurance: Medicare
LDL-C level: 140 mg/dL
BMI: 34 kg/m2
Currently on maximally
tolerated dose of atorvastatin
(40 mg) and ezetimibe
Medical history:
-
CV events: heart attack, stent placement 1 year ago
-
Additional health conditions: hypertension, metabolic syndrome, early-stage chronic kidney disease (CKD)
I want to follow my doctor's
guidance, but there are
so
many pills I have to take, it's
hard to keep track.
Instead
of adding to my at-home
medication routine,
I wish
there was another way to
lower my cholesterol.
WOULD YOU CONSIDER
LEQVIO FOR PATIENTS
LIKE CHRISTINE?
As a complement to a
maximally tolerated statin
and diet,
choose LEQVIO
for
your patients with
ASCVD
who have persistently
elevated LDL-C1
LOOKING FOR MORE INFORMATION FOR YOUR PATIENTS?
Discover resources to help
best identify
patients who
may benefit from LEQVIO
THERE'S MORE TO KNOW ABOUT LEQVIO
See what LEQVIO can do for patients like yours
STUDY CLINICAL DATA
ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; CV, cardiovascular;
CVD, cardiovascular disease; LDL-C, low-density lipoprotein cholesterol; MI, myocardial infarction.