Actor portrayal.
LEQVIO® is the only twice-yearly* PCSK9 inhibitor therapy1
2 initial doses, then 2 doses a year1
Per the LEQVIO Prescribing Information:
- No dose adjustments
- Can be taken with or without a statin—no requirement to titrate up to get to maximum tolerability before adding LEQVIO1
- No refrigeration1
- Single-dose prefilled syringe1
- Shelf life of 3 years3†
- No fasting requirements
Remember: Do not remove the needle cap until you are ready to inject.
For more information on administration, see the Instructions for Use Flash Card.
*After 2 initial doses.1
†Always check the expiration date on the prefilled syringe before administration.
After HCP administration, continuous treatment with LEQVIO is guaranteed for 6 months1*
HCP administration gives you confidence your patients received their dose.
Alirocumab is dosed every 2 weeks (75 mg-150 mg), equating to 26 injections/year.5 The monthly dose of PCSK9 mAbs is administered by giving 2 or 3 injections consecutively, which equates to 24 to 36 injections/year.4,5
This is not a complete list of all the treatments available to adults with hypercholesterolemia.
The comparison pertains only to differences in dosing and administration and should not be considered a comparison of efficacy or safety.
“I just go twice a year now. I walk out of the office, and I don’t need to think about it until the next visit.”
– Donna M., LEQVIO patient compensated for her time.
Individual results may vary.
LEQVIO administration and additional dosing information1
Not actual size.
27 gauge, 1/2-inch needle.2
- LEQVIO is a subcutaneous injection that can be given by any state-certified HCP1
- LEQVIO is administered into the abdomen, upper arm, or thigh1
- Do not remove the needle cap until you are ready to inject1
For more information on administration, see the Instructions for Use Flash Card.
Missed doses
Missed doses <3 months | Missed doses >3 months |
If a planned dose is missed by less than 3 months, administer LEQVIO and maintain dosing according to the patient’s original schedule.1 | If a planned dose is missed by more than 3 months, start a new dosing schedule—administer initially, again at 3 months, and then every 6 months.1 |
In-office administration of LEQVIO1:
- Adds minimal burden to your patient’s existing medication and care regimen
- Reduces LDL-C without adding another daily treatment
- May integrate seamlessly into your patient’s health care routine
For more information on administration, see the Instructions for Use Flash Card.
What do you need to know about LEQVIO dosing?
Learn more about LEQVIO administration including injection instructions and key product information.
HCP, health care professional; LDL-C, low-density lipoprotein cholesterol; mAb, monoclonal antibody; MOA, mechanism of action; PCSK9, proprotein convertase subtilisin/kexin type 9.